WebFeb 22, 2024 · The positive correlation of TNFR2-hnRNPK-YAP axis in HPC-like population. A, t-SNE plot of 25,189 cells from two patients with PLC. Cells were annotated on the … Heterogeneous nuclear ribonucleoprotein K (also protein K) is a protein that in humans is encoded by the HNRNPK gene. It is found in the cell nucleus that binds to pre-messenger RNA (mRNA) as a component of heterogeneous ribonucleoprotein particles. The simian homolog is known as protein H16. Both … See more This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins, and they complex with heterogeneous nuclear RNA (hnRNA). … See more Okamoto syndrome Mutations in HNRNPK cause Okamoto syndrome, also known as Au–Kline syndrome. See more AKAP1; ANKHD1; ANKRD17; ASCC1; BICC1; DDX43; DDX53; DPPA5; FMR1; FUBP1; FUBP3; FXR1; FXR2; HDLBP; HNRPK See more • Overview of all the structural information available in the PDB for UniProt: P61978 (Human Heterogeneous nuclear ribonucleoprotein K (HNRPK)) at the PDBe-KB See more HNRPK has been shown to interact with: • CSK, • DDX1, • HNRNPL, See more • Bomsztyk K, Denisenko O, Ostrowski J (June 2004). "hnRNP K: one protein multiple processes". BioEssays. 26 (6): 629–38. See more
Mechanisms of Long Noncoding RNA Nuclear Retention
WebMar 1, 2009 · The functions of hnRNPK are defined by its modular structure that allows it to interact with both nucleic acids and proteins. It has been suggested that hnRNPK serves as a docking platform that facilitates the interaction between the molecular partners involved in the processes that compose gene expression, such as transcription and translation … WebNov 1, 2024 · hnRNPK interacts with SINEB1 in Malat1 to ensure Malat1 nuclear speckle localization [46]. It also interacts with the C-rich hexamer in SIRLOIN to sequester a subset of RNAs in the nucleus [29] (Figure 3 D). However, knockdown of hnRNPK not only resulted in enhanced export of SIRLOIN-containing RNAs but also led to decreased export of … blackhillwoods.ca
The emerging roles of hnRNPK - PubMed
WebDec 7, 2024 · We identify the RNA-binding protein hnRNPK as the principal XR-PID binding factor required to recruit PCGF3/5-PRC1. Accordingly, synthetically tethering hnRNPK to Xist RNA lacking XR-PID is sufficient for Xist-dependent Polycomb recruitment. Our findings define a key pathway for Polycomb recruitment by Xist RNA, providing important insights ... Web提供全面的“Hnrnpk”相关文献（论文）下载，论文摘要免费查询，Hnrnpk论文全文下载提供PDF格式文件。Hnrnpk中文、英文词汇释义（解释），“Hnrnpk”各类研究资料、调研报告等。 WebHeterogeneous nuclear ribonucleoproteins (HnRNPs) are a group of ubiquitously expressed RNA-binding proteins implicated in the regulation of all aspects of nucleic acid … black hill whaley bridge